Product name: Follistatin 344, FST 344
Aditpotide is an experimental weight loss peptidomimetic with the amino acid sequence CKGGRAKDC-GG-D(KLAKLAK)2, which has been developed by researchers in the United States in an effort to fight obesity. Peptidomimetics are small protein-like chains designed to mimic a peptide. The peptide called Adipotide has been developed by U.S. researchers in the fight against the obesity . This experimental treatment has reduced by 11% the weight of the treated monkeys by reducing fatty tissue, the BMI, and waist circumference.
Clinical Research studies have shown that the peptide-like compound, Adipotide, is able to kill fat cells thereby causing a decrease in the volume and mass of the subcutaneous fat, and this in turn leads to weight loss. Adipotide is able to kill the adipocytes (fat cells) by selectively causing programmed cell death (apoptosis) of the blood vessels supplying the adipocytes. Due to the deprivation of nutrient supply, the subsequent starvation (which causes cellular atrophy or decrease in cell size) and the accumulation of waste products in the adipocytes; an irreversible injury occurs and this leads the mitochondria to release protease enzymes called caspases (specific factors that initiate the apoptotic process) which activate the transcription (a process whereby DNA is used to create mRNA) and translation (a process whereby mRNA is used to create the nascent primary peptide) of gene sequences which ultimately leads to the production of proteins that effect the apoptotic process.
Molecular studies have revealed that Adipotide possess a unique stereo-chemical (3D) conformation which enables it to bind to only two receptors in the body: ANXA-2 and prohibitin. These receptors are located on the surface of the endothelium (innermost wall lining) of the blood vessels supplying the white adipocytes, and as such, these receptors confer tissue specificity to adipotide. Formation of white adipocytes only occurs when the extent of energy consumption far exceeds energy utilization, and its (white adipocytes) formation and accumulation in the subcutaneous layer serves as a hallmark of obesity.
Pathological studies have shown that obesity serves a risk factor for a myriad of diseases such as cancer, hypertension, endocrine disorders (such as diabetes mellitus, hyperlipidemias and metabolic syndrome), cardiovascular disease (such as stroke and myocardial infarctions) and degenerative diseases (such as osteoarthritis). Moreover, aberrant accumulation of white adipocytes predisposes the affected individual to lipoma and lipomatosis. It is well known that abdominal adiposity is mainly caused by white adipocytes, and this form of adiposity is the most lipolytically active, thus requiring a steady blood supply. Any interference with the blood supply causes it to activate the apoptotic process.
Adipotide is an experimental treatment that prevents the blood supply to fat cells. This has helped obese monkeys to lose on average 11% of their body weight in four weeks, perhaps opening the way for therapy in humans, according to a recent research study. The study, published in the journal Science Translational Medicine , shows that body mass index and waist circumference of the rhesus monkeys were reduced.
The experimental weight loss agent, "Adipotide" used by researchers at Anderson Center consists of a substance that binds to a protein on the surface of blood vessels nourishing fat cells as well as a synthetic peptide, destroying fat cells, say the authors of the study. These cells are then metabolized by the body that destroys them and excreted. An imaging test also showed a significant reduction in fatty tissue in the bodies of these animals compared to the untreated control group, the researchers suggest the Anderson Center for Research on Cancer , University of Texas (South). " The obesity as well as smoking is a major risk factor for cancer , "says Dr. Wadih Arap, professor of medicine at the Koch Center part of the University of Texas, a major sponsor of this research.
Shown to promote weight loss in preclinical studies.
Shown to reduce symptoms of diabetes.
Novel mechanism compared to other therapeutics on the market or in trials.
No modulation of neurotransmitters, thus unlikely to have psychological side effects.
Mechanism not likely to yield GI side effects.
Our Advantages / The 7 reasons are as below: |
||
1 |
Rich experience |
Our company is a professional leading supplier in pharmaceutical and chemical area for many years. |
2 |
Suitable packagings |
The packing suits you best would be choosen to cross customs safely. Or if you have your own ideal way, it could be also taken in consideration |
3 |
High quality |
High quality guaranteed, product is tested before shipment. |
4 |
Secure shipping |
Shipping by professional forwarder Security EMS/DHL/TNT/FedEx/UPS,AusPost, |
Royal Mail express,etc.Door to door service. |
||
5 |
Fast delivery |
We have stock, so we can deliver quickly once payment isreceived. |
6 |
Quality service |
Warm aftersale service is supplied,if any question we |
will reply you within 8 hours. |
||
7 |
Competitive prices |
A discount would be given when you make a large order. VIP price for next orders. |
Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us.
Q2:How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC , TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem ,caused by us, we will send you free goods for replacement or refund your loss.
Q3: Is there any discount?
A: Yes, for larger quantity, we always support with better price.
Q4:How long does it take to the goods arrived?
A:It is Depending on your location.
Q5 Do you have any reshipment policy?
A: We have good after-sale service and re-shipment policy if the parcel lose. Our long association with our clients has brought great benefits. We always take the upmost care in the packaging of our products . Our clients will confirm this as even they struggle to find them without help at times. But in spite of our best efforts it is still possible will seize a small number of packages.
In this circumstance we promise reship free to establish long term relationship.
1. All products will have been strictly Quality Checked in house before pecking.
2. All products will be well packed before shipping.
3. Parcel can be sent out in 24 hours after payment.Tracking number available
4. Secure and discreet shipment.Various transportation methods for your choice.
5. Customs pass rate ≥99%
6. We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.
1.We have stock, so we can delivery quickly at the very day when receive the payment. Fast and discreet shipment could be arranged for customs pass Guaranteed.
2.Professional team and safe shipping method . We take responsibility to provide our customers with fast delivery and secure shipping.
3.We have efficient service, Any questions or problems after receiving the product, we will give you the best sevice.
Product name |
Specification |
anavar |
25mg*100`s |
anavar |
50mg*100`s |
winstrol |
50mg*100`s |
winstrol |
10mg*100`s |
proviron(Mesterolone) |
50mg*100`s |
dianabol |
25mg*100`s |
turinabol |
40mg*100`s |
aromasin(exemestane) |
25mg*100`s |
anadroL |
50mg*100`s |
clomid |
50mg*100`s |
nolvadex(Tamoxifen) |
20mg*100`s |
arimidex(anastrozole) |
1mg*100`s |
clenbutrol |
40ug*100`s |
2,4-dnp |
200mg*50s |
halotestin(Fluoxymesterone) |
10mg*100`s |
cialis |
20mg*100`s |
t3 |
50mcg*100`s |
cock bombs 20mg+50mg |
(20mgcials+50mg viager)*100`s |
methyltest |
10mg*100`s |
viagra |
100mg*100`s |
letrozole(femara) |
2.5mg*100`s |
Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All of our products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us.
Q2: How do you treat quality complaint?
A: First of all, our QC department will do strict examination of our export products by HPLC, UV, GC , TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q3: How to cooperate with us?
You can contact us for cooperation through the website contact information, or contact with the salesmen in our company. We will connect you about the specific detail via email.
Q4: Do you Accept Sample Order?
A: Yes, we accept small order from 1g, 100g and 1kg for your evaluation quality of our goods.
Q5: Is there any discount?
A: Yes, as for old customers and larger quantity, we always support with great discounts and surprise.
Q6: Do you accept VISA business credit card ?
A: Sorry we don't accept VISA credit card,
we'd like to accept T/T , Moneygram , Western Union.
Q7: How long does it take to the goods arrived ?
A:It is Depending on your location,
For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.
Q8: Do you have any reshipment policy ?
we have good after-sale service and re-shipment policy if the parcel lose.
Our long association with our clients has brought great benefits
We always take the upmost care in the packaging of our products
our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts it is still possible will seize a small number of packages.
In this circumstance we promise reship free to establish long term relationship
Q9: How to proceed order?
Let me konw the items, quantity and the destination contruy wihch help me to give you a right price
Please let me know the items you are looking for, quantity and the destination country. After you confirm all details of order, pay money 100% in advance and give us Shipping address. We arrange the shipment at first time after receive payment and offer you the tracking number for your goods, and we will supply after-sales service after you receive parcel.