Product Name: 2-(4-((2-(4-(Trifluoromethyl)phenyl)-5-methylthiazol-4-yl)methylthio)-2-methylphenoxy)acetic acid
Synonyms: 2-(4-((2-(4-(TRIFLUOROMETHYL)PHENYL)-5-METHYLTHIAZOL-4-YL)METHYLTHIO)-2-METHYLPHENOXY)ACETIC ACID;2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic Acid;Methyl-methyl-trifluoromethylphenyl -thiazolyl-methylsulfanyl-phenoxy-acetic Acid;2-(4-((2-(4-(trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methylthio)-2-methylphenoxy)acetic acid;GW 1516;2-(2-methyl-4-((5-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-4-yl)methylthio)phenoxy)acetic acid;GW501516, Free Acid;GSK-516
CAS: 317318-70-0
MF: C21H18F3NO3S2
MW: 453.5
Purity:99%
Appreance:Chemical Properties White Solid
Grade:Pharmaceutical Grade
Usage :For obesity, diabetes, dyslipidemia and cardiovascular disease
An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream. A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARδ agonist. Exhibits selectivity for PPARδ compared to PPARα and PPARγ. Does not exibit any activity against other nuclear or non-nuclear receptors. Reported to increase cholesterol efflux and ABAC1 expression in macrophages, fibroblasts, and intestinal cells.
KEY WORDS:Fat loss, improve endurance,no side effect,bodybuilder,cure for obesity plus helps retain lean mass,increases muscle mass.
Cardarine (GW-501516) is grouped in the category of SARMS, however in structure and definition, it is a PPAR modulator. As a PPAR modulator, it activates AMP-activated protein kinase and stimulates glucose uptake in skeletal muscle tissue. GW-501516 possesses abilities to reverse metabolism problems by stimulating fatty acid oxidation. It is considered a strong treatment for obesity and other related conditions.
GW501516 is the name of a Glaxo Wellcome drug (the GW stands for the company and the number is that of the product). It is also known as GW-501,516, GW1516, GSK-516). It is a PPARδ receptor agonist that was not taken further than clinical trials. As such it is banned in sport. It fits in a number of places on the list, including specifically as “a peroxisome Proliferator Activated Receptor δ (PPARδ) agonists (e.g. GW501516)”. But it would also come under WADA’s new catch all “non approved substances” section that aims to stop any unlicensed drug being used by athletes.
GW501516 (also known as GW-501,516, GW1516, GSK-516) is a PPAR& receptor agonist that was invented in a collaboration between Ligand Pharmaceuticals and GlaxoSmithKline in the 1990s, was entered into clinical development as a drug candidate for metabolic diseases and cardiovascular diseases, and was abandoned in 2007 because animal testing showed that the drug caused cancer to develop rapidly in several organs.
In 2007 research was published showing that high doses of GW501516 given to mice dramatically improved their physical performance; the work was widely discussed in popular media, and led to a black market for the drug candidate and to its abuse by athletes as a doping agent.
GW501516 could be used by athletes as an ergogenic performance enhancing drug that was not currently controlled by regulations or detected by standard tests. One of the main researchers from the study on enhanced endurance consequently developed a urine test to detect the drug, and made it available to the International Olympic Committee.
GW stimulates glucose uptake and skeletal muscle tissue. It burns fat by stimulating fatty acid oxidation. It's suggested as a potential treatment for obesity because of it's ability to rapidly melt fat. Also, Cardarine is said to increase HDL by an average of 79% (good cholesterol) and decrease LDL (bad cholesterol) in current Phase II trials. GW 501516 is a PPARδ agonist. These help increase your HDL levels from an enhanced expression of the cholesterol transporter ABCA1.
GW stimulates glucose uptake and skeletal muscle tissue. It burns fat by stimulating fatty acid oxidation. It’s suggested as a potential treatment for obesity because of it’s ability to rapidly melt fat. Also, Cardarine is said to increase HDL by an average of 79% (good cholesterol) and decrease LDL (bad cholesterol) in current Phase II trials. GW 501516 is a PPARδ agonist. These help increase your HDL levels from an enhanced expression of the cholesterol transporter ABCA1.
Several research studies have been conducted on rats with Cardarine (GW-501516) implementation. GW is a selective agonist, or activator, of the PPAR receptor. The binding of GW-501516 to PPAR recruits the co activator PGC-1a. The PPAR/co activator complex then up regulates the expression of proteins involved in energy expenditure.
GW-501516 has also show to increase fatty acid metabolism in skeletal muscle and protect against obesity caused from diet. Testing conducted on obese rhesus monkeys proved GW increased HDL (good cholesterol) and lowered VLDL (bad cholesterol). GW was originally intended to be created as a treatment for cholesterol problems, which it has shown to possess a high rate of efficacy in doing.
GW50156 regulates fat burning through a number of mechanisms. It increases glucose uptake in skeletal muscle tissue and increases muscle gene expression, especially genes involved in preferential lipid utilization. This shift changes the body's metabolism to favor burning fat for energy instead of carbohydrates or muscle protein, potentially allowing clinical application for obese patients to lose fat effectively without experiencing muscle catabolism or the effects and satiety issues associated with low blood sugar. GW-501516 also increases muscle mass, which improved glucose tolerance and reduced fat mass accumulation even in mice fed a very high fat diet, suggesting that GW-501516 may have a protective effect against obesity.
Cardarine is used by athletes competing in many different sports. For instance, endurance athletes may increase exercise endurance by stacking this PPAR with the AMP analog drug AICAR, or run cardarine solo. As a result, they will have a greater ability to reach higher RPM’s during their runs without hitting the maximum heart rate. This will allow the runner/cyclist/swimmer to cheat their maximum heart rates and go longer without getting winded, making this stack an incredible weapon to use in endurance sports. Actually, from personal experience I can tell that cardarine can knock over 30-45 seconds off a 5K time if used leading up to a race.
GW-501516 is taken orally. The most common dosing range for this PPAR-RA is 10-15mg per day for 8 weeks. However, some reports state the medication needs to be used for 12 weeks for optimal results, with 20mg per day being well tolerated by most individuals.
Not to say that there are none, but in the last 20 years no side effects have been seen by anyone studying the drug.
GW501516 has not only been tested in healthy subjects, but also those with simulated "real life" habits (such as drinking alcohol, stimulant narcotics, and the use of tobacco products). It is uncertain if there are long term ramifications, but no research has been published stating otherwise.
This is what makes Cardarine so incredibly popular and usable over long periods of time. In certain studies, there have even been signs showing the reversal of diabetes, obesity, Dyslipidemia and many other diseases.
Not to say that there are none, but in the last 20 years no side effects have been seen by anyone studying the drug.
GW501516 has not only been tested in healthy subjects, but also those with simulated "real life" habits (such as drinking alcohol, stimulant narcotics, and the use of tobacco products). It is uncertain if there are long term ramifications, but no research has been published stating otherwise.
This is what makes Cardarine so incredibly popular and usable over long periods of time. In certain studies, there have even been signs showing the reversal of diabetes, obesity, Dyslipidemia and many other diseases.
|
Our Advantages / The 7 reasons are as below: |
||
|
1 |
Rich experience |
Our company is a professional leading supplier in pharmaceutical and chemical area for many years. |
|
2 |
Suitable packagings |
The packing suits you best would be choosen to cross customs safely. Or if you have your own ideal way, it could be also taken in consideration |
|
3 |
High quality |
High quality guaranteed, product is tested before shipment. |
|
4 |
Secure shipping |
Shipping by professional forwarder Security EMS/DHL/TNT/FedEx/UPS,AusPost, |
|
Royal Mail express,etc.Door to door service. |
||
|
5 |
Fast delivery |
We have stock, so we can deliver quickly once payment isreceived. |
|
6 |
Quality service |
Warm aftersale service is supplied,if any question we |
|
will reply you within 8 hours. |
||
|
7 |
Competitive prices |
A discount would be given when you make a large order. VIP price for next orders. |
Hjtc (Xiamen) Industry Co., Ltd.
Xiamen Huayongjian Biotechnology Co., Ltd.
Contacts: June & Eason
Whatsapp:+8618206063252; +8618759200098
E-mail: june@steroidpowder-hjtc.com;
eason@steroidpowder-hjtc.com
Web site:https://www.steroidpowder-hjtc.com/
http://www.safeststeroid.com/
http://www.glassviallabels.com/
https://hjtc-printing.en.made-in-china.com/
| ID | Item | Capacity |
| 1 | Testosterone Cypionate | 250mg/ml |
| 2 | Testosterone Enanthate(TE250) | 250mg/ml |
| 3 | Testosterone Enanthate(TE300) | 300mg/ml |
| 4 | Testosterone Undecanoate (TU250) | 250mg/ml |
| 5 | Testosterone Propionate | 100mg/ml |
| 6 | Testosterone Propionate | 200mg/ml |
| 7 | Testosterone Propionate | 250mg/ml |
| 8 | Testosterone Sustanon(TS) | 100mg/ml |
| 9 | Testosterone Base(Test Base) | 100mg/ml |
| 10 | SU-400(TP,TIS,TPP,TDECA) | 400mg/ml |
| 11 | Sustanon 250(TP,TIS,TPP,TDECA) | 250mg/ml |
| 12 | Testosterone Blend300(TE,TP) | 300mg/ml |
| 13 | Testo-600(TA,TPP,TC) | 600mg/ml |
| 14 | TRA100(Tren Acetate) | 100mg/ml |
| 15 | TRE100(Tren Enanthate) | 100mg/ml |
| 16 | TRE200(Tren Enanthate) | 200mg/ml |
| 17 | TRX100(Tren Hex Carbonate) | 100mg/ml |
| 18 | Trenmix200(TRA,TRE) | 200mg/ml |
| 19 | TRB50(Tren Base) | 50mg/ml |
| 20 | Tren Suspension(Trenbolone Suspension) | 100mg/ml |
| 21 | Blend300(TRA,DP,TP) | 300mg/ml |
| 22 | Blend375(TRE,DE,TE) | 375mg/ml |
| 23 | Blend500(TRE,DE) | 500mg/ml |
| 24 | Methenolone Enanthate (Primobolan Enanthate ) | 100mg/ml |
| 25 | Methenolone Enanthate (Primobolan Enanthate ) | 200mg/ml |
| 26 | DECA200(Nandrolone Decanoate) | 200mg/ml |
| 27 | DECA300(Nandrolone Decanoate) | 300mg/ml |
| 28 | NANDROMIX-300(NPP,DECA) | 300mg/ml |
| 29 | NPP100(Nandrolone Phenypropionate) | 100mg/ml |
| 30 | NPP200(Nandrolone Phenypropionate) | 200mg/ml |
| 31 | Stanozolol Oil Base | 50mg/ml |
| 32 | Stanozolol Oil Base | 100mg/ml |
| 33 | Stanozolol Suspension | 50mg/ml |
| 34 | Stanozolol Suspension | 100mg/ml |
| 35 | BU200(Boldenone Undecylenate,Equipoise) | 200mg/ml |
| 36 | BU300(Boldenone Undecylenate,Equipoise) | 300mg/ml |
| 37 | BU600(Boldenone Undecylenate,Equipoise) | 600mg/ml |
| 38 | Maseron 100(Drostanolone Propionate,DP) | 100mg/ml |
| 39 | MAST200(Drostanolone Enanthate,DE) | 200mg/ml |
| 40 | Dianabol 50(Methandrostenolone) | 50mg/ml |
| 41 | DHB(1-Testosterone Cypionate) | 100mg/ml |
| 42 | MENT50(Trestolone Acetate) | 50mg/ml |
| 43 | Stanolone(DHT) | 50mg/ml |
| 44 | Stanolone(DHT) | 100mg/ml |
| 45 | Superdrol 50(Methyldrostanolone) | 50mg/ml |
| 46 | Superdrol 100(Methyldrostanolone) | 100mg/ml |
| 47 | Metribolone | 5mg/ml |
Packaging: 10ml/vial,10vial/box(Aluminum foil bag) ,10vial/box(Aluminum foil bag)
Storage:Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Delivery:Usually within3-5 working days after full payment.
Shipping:EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA, DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service;Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;For high value products, please select air shipping and DHL express for safe.The package are all privacy and safety, fast and safe transportation, there's waybill number can track the movement of the goods
Q1:How to confirm the Product Quality before placing orders?
A:free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
Q2:Can you give me a discount price?
A:Surely,It depend on your qty.Larger order can enjoy cheaper price.
Q3:When you ship my order?
A:Normally within 2 to 3 days after confirming your payment,because we need time to arrange Stealth Packing for 100% customs clearance.
Q4:Can you guarantee I can get my goods without any custom problem?
Yes, We have Reship Service.You can get your goods without any problem.
Q5:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us,we will send you free goods for replacement or refund your loss.
Q6:Which kind of payment terms do you accept?
A:For any order,you can pay by Paypal,Bitcoin,T/T,Western Union or Money Gram.
Q7: How to contact with us?
A:We use email, whatsapp, wickr me, wechat,ect. so pls be free to contact me if you have any needs.
