LGD-4033 is rapidly increasing in popularity, as it has shown to be the strongest and most anabolic-like SARM in existence up to this point. SARMS are quite different from steroids in terms of their makeup, lack of side effects and recovery time. SARMS can be run much longer than oral steroids. They are non-methylated and don't pressure the liver. Although the results are not as drastic as some steroids, they are much cleaner, more keepable and have several properties that are extremely desirable that steroids may not be able to provide.
LGD-4033 is a selective androgen receptor modulator (SARMS), and a novel non-steroidal oral SARM that binds to AR with high affinity (Ki of ~1 nM) and selectivity. It's in a class of androgen receptor (AR) ligands that is tissue selective, developed to treat muscle wasting associated with cancer, acute and chronic illness and age-related muscle loss. LGD-4033 is expected to produce the therapeutic benefits of testosterone with improved safety, tolerability and patient acceptance due to tissue-selective mechanism of action and an oral route of administration.
Ligandrol is an orally active nonsteroidal SARM developed by Ligand Pharmaceuticals that has completed Phase I clinical trials which involved multiple ascending doses in healthy volunteers.According to the National Institute of Health's U.S. National Library of Medicine, in Phase I clinicaltrials "Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects." These clinical trials showed that humans could safely tolerate up to 22mg/day of this compound for 14 consecutive days; this compound contributed to increases in lean body mass, decreases in fat mass,increases in strength, as well as an increases in senses of well-being.
Ligandrol also appears to decrease bone turnover rate, which appeals to those with osteoporosis. Based on these findings, it appears that LGD4033 is an excellent SARM for bulking, cutting, recomposition, or strength-gain phases.
LGD4033, LGD - Unparalleled for very lean bulking. 3 weeks of just 1mg per day can add nearly 4 pound of lean mass without exercise, in males. Usual dose is 2.5-10mg, beyond that, you're asking for hypoglycemia and other issues.
There's very little point to anything beyond that, for most people the diminishing returns begin at 5mg. It loads your muscles full of water and glycogen, rapidly increasing the amount of exercise volume you can do at any given percentage of your max. My best example is that when my squat max was 355, my 20rm was 245 easily after 20 rep set of 225. Pumps are insane, and most users have a significant appetite increase and nutrient demand.
During my long term use of this, I retained much of the nutrient partitioning effects for some time after the cycle. I think there may be some gene expression change toward building muscle that LGD affects. I noticed similar difficulty losing fat however, mild caloric restriction absolutely destroyed my energy.
LGD-4033 is a selective androgen receptor modulator a novel non-steroidal, oral SARM that binds to AR with high affinity (Ki of ~1 nM) and selectivity, class of androgen receptor (AR) ligands that is tissue selective, developed to treat muscle wasting associated with cancer, acute and chronic illness and age-related muscle loss. LGD-4033 is expected to produce the therapeutic benefits of testosterone with improved safety, tolerability and patient acceptance due to tissue-selective mechanism of action and an oral route of administration.
LGD-4033, like other popular SARMS, is very versatile and has a list of benefits no matter the goal of the user. Whether it's lean muscle mass, maintenance of your hard earned gains during a cutting cycle, or bridging the gap between steroid cycles, LGD-4033 can be a very beneficial tool.Studies suggest that this SARM will lend therapeutic benefit to many testosterone deficiency conditions. In fact, it's not unheard of to hear of improvements in joint pain or nagging injuries after starting a course of Anabolicum (LGD), much like its cousin Ostarine (MK-2866). In addition,LGD can increase strength, vascularity, and fat loss while bulking, and it can help during"recomposition" (recomp).
Anabolicum (LGD), like other popular SARMS, is very versatile and has a list of benefits no matter the goal of the user. Whether it's lean muscle mass, maintenance of your hard earned gains during a cutting cycle, or bridging the gap between steroid cycles, LGD-4033 can be a very beneficial tool.
Studies suggest that this SARM will lend therapeutic benefit to many testosterone deficiency conditions. In fact, it's not unheard of to hear of improvements in joint pain or nagging injuries after starting a course of Anabolicum (LGD), much like its cousin Ostarine (MK-2866). In addition, LGD can increase strength, vascularity, and fat loss while bulking, and it can help during "recomposition" (recomp).
For Bulking
Suggested dosage is 5-10 mg a day for 8 weeks. A protein-rich diet is also necessary as well as higher caloric intake if you plan to beef up by 10 pounds or more.
For Cutting
Use LGD-4033 with SARMS triple pack (GW-501516, S-4 and LGD-4033) to make it more effective as you are aiming to add more size while cutting fat. Suggested dosage is 3-5 mg a day for 8 weeks.
For Recomping
LGD-4033 is best used for recomping. Many users have said that they've observed a boost in lean body mass and fat loss. Using it together with other SARMS such as GW-501516 or Cardarine will give you a stronger and better recomp. Suggested dosage is 5-8 mg per day for 8 weeks.
LGD-4033 is most commonly recommended at 5-10mg per day with once daily dosing schedule.The half-life of LGD 4033 is between 24-36 hours. It has been found to be well tolerated at up to 22mg/day in people.
The half life of LGD is quite long compared to other SARMs - between 26 and 38 hours. LGD is extremely potent, so a small dose is all that is necessary - the average dose is 10mg per day, and length of cycle is typically 8 weeks. Nonetheless, the dosage range is subject to users discretion, going as low as 2mg per day and up to 20mg.
Regarding the adequate use of LGD in liquid form, it should be swallowed - simply squirt the liquid into the mouth, swallow immediately, then chase down with some juice or water as the taste can be unpleasant. It is not necessary to hold SARMs under the tongue, and you should never mix them in a cup with other liquids.
| SARM | CAS.NO. |
| Ostarine / MK-2866 | 841205-47-8 |
| Andarine S4 / GTX-007 | 401900-40-1 |
| GW-501516 / Cardarine | 317318-70-0 |
| LGD-4033 / Ligandrol | 1165910-22-4 |
| MK-677 / Ibutamoren | 159752-10-0 |
| SR9009/SR9011 | 1379686-30-2 |
| RAD140 | 118237-47-0 |
| YK11 | 431579-34-9 |
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