Good Quality Sarms(RAW) - Bodybuilding SR9011 Increase Exercise Endurance CasNO.1379686-29-9 Quick Effect – Hjtc Detail:
Product Name: SR9011
Other name:Stenabolic
CAS: 1379686-29-9
Grade: Pharmaceutical grade
Molecular formular: C20H24ClN3O4S
Molecular Weight: 437.94
purity: 99%
Original: China
Appearance: White powder
Application: SR9011 increase exercise endurance and loss weight.
Usage:reduce mass fat
SR9011 is a trifunctional methacrylate monomer that provides exceptional adhesion to metal substrates. SR9011 is recommended for use in peroxide cured coatings, sealants, and PVC-based plastisols. Usage levels of 5% to 10% by weight are recommended.SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB- with an EC50 ~790 nM and REV-ERB-with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB- and REV-ERB- play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure.
SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.
SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic.
The difference between SR9009 and other diet pills is in its chemistry. SR9011 is not an appetite suppressant-as many weight-loss drugs are-and directly works by increasing the metabolic rate of muscle. Your metabolism speeds up and slows down naturally during the day, meaning that sometimes food is used for energy and sometimes it’s stored as fat. By re-synching a dysfunctional metabolic clock, SR9011 ensures that food and excess fat are used as energy. SR9011 is one of a pair of compounds developed at TSRI by Burris and his team. The drug binds to Rev-erbα,a natural protein in the body that influences lipid and glucose metabolism in the liver, inflammatory responses, and fat-storing cells. By binding to Rev-erbα, SR9011 can kickstart metabolism with another pleasant side-effect: increased muscle strength.
The new compounds known as SR9011 can increase laboratory metabolism, fat burning and muscle growth. Scientists at the Scripps Institute (TSRI) have successfully tested a drug called SR9011, In mice that initiate metabolism and lead to increased muscle development. In essence, this is a pill of the sport system. SR9011 changes the metabolic characteristics of skeletal muscle in a similar manner to the observed changes, Animal training has endurance. Basically, the drug sends a signal to the muscle and tells it to modify it Its metabolism. Half of the mice studied showed improved run endurance in terms of time and distance. Obviously, a small drug-like molecule can increase the metabolic rate of skeletal muscle, increase exercise tolerance.
Product name | sr9009 | |
Appearance | White powder | |
Absorbance | ≤0.30% | Conform |
Specific Rotation | +39°~ +43° | +40.2° |
Chromatography Purity | Conform | Conform |
17α-Isomer | ≤0.50% | 0.38% |
Organic Volatile Impurities | Conform | Conform |
Loss On Drying | ≤0.50% | 0.27% |
Residue On Ignition | ≤0.10% | 0.015% |
Assay | 97~101% | 99.5% |
1. 1/3 as androgenic as testosterone in muscle tissue
2. Anabolic at doses above 50mg
3. Great for strength
4. Great for muscle hardness
5. Great for enhanced vascularity
6. Great for endurance (aerobic or anaerobic)
7. Accelerated fat loss above 50mg
8. Joint healing effects
1, High quality with competitive price:
1) Standard: U.S Standard
2) All Purity≥99.8%
3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcel can be sent out within 8 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
3) Customs pass rate ≥99.8%
4)We provide re-ship policy.
5) We have warehouse in Australia, Canada and England, we have large amounts of stock in the warehouse, can ship to you directly from our foreign warehouse!
3, We have clients throughout the world.
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Meeting customers’s requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
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1 | Clenbuterol | 40mcg*100/bottle |
2 | Clomid(Clomiphene) | 50mg*100/bottle |
3 | Letrozle(Femara) | 2.5mg*100/bottle |
4 | Halotestin(Fluoxymesterone) | 10mg*100/bottle |
5 | Dianabol(Methandrostenolone) | 10mg*100/bottle |
6 | Dianabol(Methandrostenolone) | 20mg*100/bottle |
7 | Dianabol(Methandrostenolone) | 50mg*100/bottle |
8 | Proviron(Mesterolone) | 10mg*100/bottle |
9 | Proviron(Mesterolone) | 25mg*100/bottle |
10 | Primobolan(Methenolone Acetate) | 10mg*100/bottle |
11 | Primobolan(Methenolone Acetate) | 25mg*100/bottle |
12 | Primobolan(Methenolone Acetate) | 50mg*100/bottle |
13 | Superdrol(Methasterone) | 10mg*100/bottle |
14 | T3(Liothytonine Sodium) | 25mcg*100/bottle |
15 | T3(Liothytonine Sodium) | 40mcg*100/bottle |
16 | T4 | 40mcg*100/bottle |
17 | Anavar(Oxandrolone) | 10mg*100/bottle |
18 | Anavar(Oxandrolone) | 25mg*100/bottle |
19 | Anavar(Oxandrolone) | 50mg*100/bottle |
20 | Anadrol(Oxymetholone) | 50mg*100/bottle |
21 | Winstrol(Stanozolol) | 10mg*100/bottle |
22 | Winstrol(Stanozolol) | 20mg*100/bottle |
23 | Winstrol(Stanozolol) | 50mg*100/bottle |
24 | Turinabol(Chlordehydromethyltestosterone) | 10mg*100/bottle |
25 | Turinabol(Chlordehydromethyltestosterone) | 25mg*100/bottle |
26 | Nolvadex(Tamoxifen) | 10mg*100/bottle |
27 | Nolvadex(Tamoxifen) | 20mg*100/bottle |
28 | Aromasin(Exemestane) | 25mg*100/bottle |
29 | Arimidex(Anastrozole) | 1mg*100/bottle |
30 | Viagra(Sildenafil) | 100mg*100/bottle |
31 | Cialis(Tadanafil) | 20mg*100/bottle |
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By Linda from Nigeria - 2018.06.18 17:25
The customer service staff's attitude is very sincere and the reply is timely and very detailed, this is very helpful for our deal,thank you.
By Eleanore from Houston - 2017.12.31 14:53