China wholesale Clomiphene Citrate(Clomid) - GMP Factory Direct Supply 99% Purity Anastrozole(arimidex) Raw Powder CAS: 120511-73-1 – Hjtc Detail:
Anastrozole is also called Arimidex, it can be referred to as an aromatase inhibitor which helps prevent estrogen production in females. Research has shown that the estrogen hormone is responsible for the creation of breast cancer tumors in women. Arimidex is the drug administered to intercept the enzyme aromatase, which is a substance that assists the body tissues in producing estrogen. Arimidex is a popular drug in the battle against breast cancer. It is by and large, a hormonal treatment which can prevent the recurrence of breast cancer.
Arimidex is known to have diminished estrogen way too much in some patients. This is why blood tests or salivary tests are recommended after a week of usage to determine whether the dosage is appropriate.Arimidex tends to work quite differently than the traditional anti-estrogens. Anti-estrogens like Clomid or Nolvadex tend to intercept estrogen receptors in certain tissues while activating them in others. Meanwhile, Arimidex directly intercepts the enzyme aromatase. When a patient has been recommended the use of Arimidex, Clomid use along with is unnecessary. Doing so mayhave some benefits.
Arimidex is generally used for all stages and forms of breast cancer which are classified to be estrogen receptor positive. In case the patient has estrogen receptor negative or triple negative cancer, the usage of Arimidex is unlikely to help.
Arimidex is sometimes used to treat male breast cancer, but it has not been well studied in men.Arimidex been studied for use by infertile men to balance testosterone levels and maintain a healthy sperm count.Some male athletes and bodybuilders who take anabolic steroids to build muscle also take Arimidex to reduce the estrogen production that is a side effect of steroid use.
Arimidex is highly suitable for solving either problem.
With correctly chosen dosing, free estradiol level can be brought fairly accurately to a desired range. When not using anabolic steroids, for most men I recommend about 20-29 pg/mL for best effect on mood, performance, libido, and long term health and to provide excellent benefit to natural testosterone production.
Anastrozole has a half life of about two days. For this reason, when use is ongoing, on taking a dose of Arimidex the user will have in his system not only the dose that he just took, but also about another two days’ worth that has built up in his system. If just starting usage, however, there is no such buildup and effect will be less.
Test Items |
Specification |
Results |
Description |
White crystalline powder |
Complies |
Total Impurity |
max.0.5% |
0.18% |
Total Unspecified Impurity |
max. 0.2% |
0.08% |
Individual unspecified impurlty |
max. 0.1% |
0.05% |
Related compound B |
max. 0.2% |
0.07% |
Related compound C |
max. 0.2% |
0.04% |
Related compound D |
max. 0.1% |
0.05% |
Related compound E |
max. 0.1% |
0.06% |
Limit of cyclohexane |
max. 0.08% |
0.05% |
Limit of ethylacetate |
max. 0.1% |
0.07% |
Melting point |
81.0~84.0ºC |
82.5~83.2ºC |
Water |
max. 0.3% |
0.21% |
Residue on ignition |
max. 0.1% |
0.07% |
Heavy Metals |
max.0.001% |
Complies |
Assay (HPLC) |
98%~102% |
99.2% |
Conclusion |
It complies to USP32 Standard |
Anastrozole lowers the amount of oestrogen in the body. The female sex hormones oestrogen and progesterone stimulate many breast cancers to grow. Lowering the level of oestrogen can stop or slow the growth of breast cancer cells.
Anastrozole blocks a process called aromatisation which changes sex hormones called androgens into oestrogen. This happens mainly in the fatty tissues, muscle and the skin and needs a particular enzyme called aromatase.
An aromatase inhibitor. Used as an antineoplastic raw materials.Potent selective triazole aromatase inhibitors, can inhibit the cytochrome P-450 aromatase enzyme which depends blocking the biosynthesis of estrogen, and estrogen to stimulate breast cancer cell growth factors. Treatment of breast cancer, especially for those with hormone relapse after adjuvant therapy after menopause for women with advanced breast cancer.
The drug is appropriately used when using substantial amounts of aromatizing steroids, or when one is prone to gynecomastia and using moderate amounts of such steroids. Arimidex does not have the side effects of aminoglutethimide (Cytadren) and can achieve a high degree of estrogen blockade, much moreso than Cytadren. It is possible to reduce estrogen too much with Arimidex, and for this reason blood tests, or less preferably salivary tests, should be taken after the first week of use to determine if the dosing is correct.
Dosages of arimidex will vary from person to person. This is why blood work is essential to finding the perfect balance. One should start out at half a mg every other day and adjust as needed for the cycle. Some AAS users will not use an AI at first but they will have it on hand just in case. This isn’t always a good idea, as once you start noticing gyno or excessive water weight it could be too late to reverse. Since AAS will continue building in the body and aromatize, taking arimidex at this point would be like trying to stop a car already in motion.
General Dosage For Men: 0.5 mg per day or every other day
Aromatase inhibition is the gold standard for treatment of early and advanced breast cancer in postmenopausal women suffering from an estrogen receptor-positive disease. The currently established group of anti-aromatase compounds comprises two reversible aromatase inhibitors (anastrozole and letrozole) and on the other hand, the irreversible aromatase inactivator exemestane. Although exemestane is the only widely used aromatase inactivator at this stage,physicians very often have to choose between either anastrozole or letrozole in general practice.These third-generation aromatase inhibitors Letrozole and Anastrozole, have recently demonstrated superior efficacy compared with tamoxifen as initial therapy for early breast cancer improving disease-free survival.
However, although anastrozole and letrozole belong to the same pharmacological class of agents (triazoles), an increasing body of evidence suggests that these aromatase inhibitors are not equipotent when given in the clinically established doses. Preclinical and clinical evidence indicates distinct pharmacological profiles. Thus, this review focuses on the differences between the non-steroidal aromatase inhibitors allowing physicians to choose between these compounds based on scientific evidence. Although we are waiting for the important results of a still ongoing head-to-head comparison in patients with early breast cancer at high risk for relapse, clinicians have to make their choices today.
On the basis of available evidence summarised here and until FACE-data become available, letrozole seems to be the best choice for the majority of breast cancer patients whenever a non-steroidal aromatase inhibitor has to be chosen in a clinical setting.
Hjtc (Xiamen) Industry Co., Ltd. is a professional new-typeSupplier of the Pharmaceutical Packaginga &Steroids Raw Materials .It’s factory located in hubei province.Our company enjoyed great reputation both domestic and abroad under the belief of “Integrity management,Quality controlling and Customer orientation”.The company’s competitive product is Pharmaceutical Raw Materials and intermediates, In recent years, the company has made a major breakthrough in steroids raw powder.our product fit national ISO9001 and ISO2000 standards and we are usually exported to North and South America, Europe,the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.
Q1:How to confirm the Product Quality before placing orders?
A:free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
Q2:Can you give me a discount price?
A:Surely,It depend on your qty.Larger order can enjoy cheaper price.
Q3:When you ship my order?
A:Normally within 2 to 3 days after confirming your payment,because we need time to arrange Stealth Packing for 100% customs clearance.
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Yes, We have Reship Service.You can get your goods without any problem.
Q5:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us,we will send you free goods for replacement or refund your loss.
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