Exemestane is a steroidal Aromatase Inhibitor (AI) that is most commonly known as Aromasin. In fact, the Aromasin brand name is the only pharmaceutical grade brand of the Exemestane AI due to the tight patent Upjohn has maintained on the product. While tightly controlled by the pharmaceutical giant, Aromasin is available in numerous countries around the globe.The primary purpose of use as with most AI's would be to combat breast cancer in post-menopausal women. Shortly after, the AI would begin to gain a lot of popularity among anabolic steroid users for its ability to protect against estrogenic related side effects. This action is very similar to the older and more popular AI's in Arimidex and Femara It would also gain a fair amount of popularity in Post Cycle Therapy (PCT) plans among steroid users. It was not the first AI to gain such popularity but would prove to be a little more advantageous for this purpose than most AI's.
Aromasin is officially classified as a steroidal suicide Aromatase Inhibitor, and carries the ability to inhibit the aromatase enzyme, which is responsible for the production or conversion of testosterone to estrogen. Aromasin has the ability to block aromatization, which in turn inhibits the production of estrogen, and thereby lowers the body's serum estrogen levels. This will prove useful to breast cancer patients as breast cancer often feeds off the estrogen hormone. It will also prove useful to the anabolic steroid user.
Many anabolic steroids have the ability to increase estrogen levels due to the aromatase process, specifically the conversion of testosterone to estrogen. This can lead to gynecomastia and water retention. Excess water retention can also promote high blood pressure when it becomes severe. Steroids that do not carry a strong estrogenic nature can also cause these effects, most notably gynecomastia if they carry a progestin nature. A prime example would be Nandrolone, which while it aromatizes only does so at 20% the rate of testosterone. However, it also carries a strong progestin nature, and progesterone has been well noted for carrying the ability to stimulate the estrogenic mechanism in the mammary tissue. By administering Aromasin during the use of anabolic steroids, this will inhibit the aromatase process, lower estrogen levels and protect the individual from estrogenic side effects. The product claims on average to have the ability to lower serum estrogen levels by 85%.
Exemestane is used to fight breast cancer and raise testosterone in the body.Exemestane blocks the process of aromatisation. So it lowers the amount of estrogen in the body. In early breast cancer, taking exemestane can help to stop breast cancer coming back. In advanced breast cancer the cancer cells may grow more slowly or stop growing completely.
It blocks the enzyme aromatase, which is used to convert androgens into estrogen. In the absence of estrogen, tumors dependent on this hormone for growth will shrink
1. It is one of the most powerful estrogen suppressing compounds.
2. It is one of the best compounds to lower the aromatizing effect of steroids.
3. It is available for body builders taking anabolic steroids.
4. It acts by blocking the enzyme aromatase, subsequently blocking the production of estrogen.
5. It is also a kind of antineoplastic (hormonal) raw materials.
Test Items | Specification | Results |
Description | White crystalline powder, odorless | Conforms |
Solubility | Easily soluble in water, unsoluble in ethanol | Conforms |
PH | 6.0~7.5 | 6.9 |
Solution clarity and color | solution should be clear and colorless | Conforms |
Related substances |
5’CMP 0.3% Simple impurity Total other impurity |
0.01% 0.03% 0.10% |
Chloride | 0.05% | Conforms |
Ammonium | 0.05% | Conforms |
Fe | 0.01% | Conforms |
Phosphate | 0.1% | Conforms |
Loss on drying | ≤6.0% | 1.3% |
Heavy metals | 0.002% | Conforms |
Arsenide | 0.0001% | Conforms |
Bacterial Endotoxins | 0.3EU/mg | Conforms |
Microbial Limit | Conforms | Conforms |
Assay(on dried basis) | ≥98.0% | 99.8% |
Anti-Estrogen Series | |
Tamoxifen Citrate (Nolvadex) | Dutasteride (Avodart) |
Clomifene Citrate (Clomid) | Finasteride (Proscar) |
Letrozole (Femara) | Formestane (Lentaron) |
Toremifene Citrate (Fareston) | Cabergoline (Caber) |
Exemestane (Aromasin) | Raloxifene Hydrochloride |
Anastrozole (Arimidex) | Pramipexole |
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Hjtc (Xiamen) Industry Co., Ltd.
Xiamen Huayongjian Biotechnology Co., Ltd.
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