Product Name:Mechano Growth Factor,MGF
MF: C121H200N42O39
MW: 2888.16
Purity: 99%
Specification: 2mg/vial
Appearance: White Lyophilized Powder
Grade:Pharmarceutical Grade
2 kinds of MGF splice variants of IGF
Mechano Growth Factor (MGF) also known as IGF-1Ec is a growth factor/repair factor that is derived from exercised or damaged muscle tissue. It’s called MGF as IGF-IEa is a bit of a mouthful and harder to identify amongst the other IGF variants.
IGF-1Ec:This is the first phase release igf splice variant and it appears to stimulate satellite cells into activation, This is the closest variant to synthetic MGF.When mechanical overload is introduced to a muscle (as by weight training), the IGF-1 gene released and is differentially spliced during the bodies response. Initially, it it is spliced to produce predominantly IGF-1Ec (called the MGF splice variant of IGF-1). This early splicing stimulates satellite cells into activation. Which in turn allows the activation of extra undamaged nuclei to grow new muscle fiber and tissue. The appearance of MGF also initiates the upregulation of new protein synthesis.
IGF-1Ea:After this initial splicing of IGF-1 into MGF, production then switches towards producing a systemic release of IGF-1Ea from the liver, which also upregulates protein synthesis as well. It is the secondary release of igf from the liver, and its far less anabolic and shorter acting.
The expression of IGF-1 splice variants, over the course of the healing and regrowth phase of muscle repair is thought to be the primary anabolic mechanism by which the body produces new muscle. MGF is available as an injectable peptide, and it has been anecdotally shown that injecting it will cause a response in the area resulting in localized muscle growth.
MGF is a splice variant of the IGF gene which increases stem cell count in the muscle and allows for muscle fibers to fuse and mature. This is a process required for growth of adult muscle. Natural MGF is made locally and does not travel into the bloodstream. Synthetic MGF is water based and when administered intramuscularly, travels into the bloodstream. MGF is only stable in the blood stream for only a few minutes.
In bodybuilding this drug is used to accelerate muscle growth. Other effects of the drug include decrease of fat mass of the body, endurance increase, improvement of immune defenceand skin, bone strengthening, lowering of cholesterol level, accelerated recovery. Those who administered MGF declared that they experienced no side effects, which frequently occur with the use of other drugs for gaining body mass.
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When you train, what happens to your muscles is they break down, the cells are damaged, muscle tissue needs to be repaired and your body produces 2 forms of MGF splice variant. The first initial release of the above mentioned number 1 variant from the liver helps muscle cell recovery, if there is no MGF then muscle cells die.
As muscle is a post-mitotic tissue and as such cell replacement is not a means of tissue repair, if the cells are not repaired they die and your muscles get smaller and weaker. In muscle tissue, the pool of these stem cells is apparently replenished by the action of MGF, which is produced as a pulse following damage.
Now, with synthetic injections of MGF you can increase the pulse and so speed up recovery, and increase the muscle tissue cells by stimulating satellite cells into full maturity. In terms of dosages, 200mcg bi-laterally is the very best choice of dosing in muscles trained.
MGF, short for Mechano Growth Factor is one of the most recent craze in the bodybuilding community. It has been used by bodybuilders, athletes and sportsmen alike due to its purported anabolic effects which promotes increased muscle mass, lean muscles, physical performance and fat loss. This profile overview are the things that you must know before purchasing or using MGF.
Despite its anabolic activity, many people prefer PEG MGF than buying MGF. This is so as MGF has very short half-life lasting with 5 to 7 minutes only. Moreover, it should be used immediately after workout or physical activities as it wouldn't work with an undamaged muscle tissue. Still, it may be an effective treatment for individuals suffering from muscle wasting medical conditions.
MGF was first discovered by a group of researchers in the human muscle. It is also known as IGF-1Ec. MGF is a repair factor or growth factor that is derived from a muscle tissue that has been damaged or injured. It is also found on exercised muscle tissues.
Compared to other IGF variants, MGF is very special because of its role in muscle growth and development. Research and anecdotal evidence has shown that it is able to help with the regrowth and improvement of wasted or atrophied tissues through increasing the regulation of protein synthesis and activating the stem cells found in the muscles. Its exceptional ability to help in muscle regrowth can help in lessening speed of recovery whilst increase muscle growth.
Furthermore, MGF is able to activate stem cells through initiating muscle satellite cell activation alongside its ability to improve its IGF-1 receptor activities. As a direct result, MGF is able to improve turnover of protein synthesis. Hence, if MGF is used efficiently and correctly, it could greatly help in increasing muscle mass over time.
Before explaining how synthetic MGF works, you must know that the liver naturally produces two types of MGF splice variants. The first one is IGF-1Ec. IGF-1Ec stimulates your satellite cells to be activated and it is considered to be the closest IGF variant of the synthetic MGF. The second MGF splice variant is IGF-1Ea. Compared to IGF-1Ec, IGF-1Ea is far less anabolic.
Synthetic MGF only works in the body after the introduction of mechanical overload towards your muscles (e.g. after weight training or heavy workouts). When your muscle is subjected to exercise or injury, IGF-1 gene is released which is then spliced as an immediate response of your body. Primarily, the early splicing stimulates the activation of satellite cells allowing the stimulation of undamaged cells to grow new muscle tissues and fibers. The presence of MGF also helps with the upregulation of protein synthesis. After which, systemic release of IGF-1Ea from your liver occurs - a process that also helps with the upregulation of protein synthesis within your body. Simply put it, the primary anabolic mechanism of MGF is related to the release of IGF-1 splice variants during muscle regrowth and healing.
| Product Name: | MGF |
| Unit size: | 2 mg/vial |
| CAS NO.: | 62031-54-3 |
| Synonyms: | MGF, Mechano Growth Facto*, |
| Sequence: | Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-Arg-Lys |
| Purity: | ≥99% (HPLC) |
| Physical State: | Lyophilized Powder |
| Solubility: | Soluble in water or 1% acetic acid |
| Storage: | Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18°C. Upon reconstitution of the peptide it should be stored at 4°C between 2-21 days and for future use below -18°C. |
HPLC Report:>98.59%
MS Report
Training, bodybuilding and extreme physical activities causes muscle breakdown and muscle tissue & cells damage. Note that human muscles are post-mitotic tissues, hence, cell replacement is not a viable option for tissue repair. If your body is unable to repair your damaged muscle cells, they die leading to weaker and smaller muscles. Apparently, MGF is able to stimulate muscle regrowth and development.
Injection of synthetic MGF could help increase the speed of your recovery from muscle injury. It could also increase your muscle cells through stimulating your satellite cells into maturity. To achieve this, you must use MGF in proper dosages and as recommended by manufacturers.
Generally, there have been no reports of extreme side effects associated with MGF use. Nonetheless, prospective users must ensure that they take extreme precautions in using this substance particularly that it is administered via parenteral route. It is also advised that MGF at recommended dosages only. Some authors recommend 200 mcg of MGF used bilaterally.
Although considered generally safe to use, individuals suffering from any medical condition or are taking any prescribed/OTC/herbal medications should consult their physicians first. Lactating and pregnant mothers should also not use MGF.
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| MGF | 2mg/vial | |
| PEG-MGF | 2mg/vial | |
| CJC1295 with DAC | 2mg/vial | |
| CJC1295 without DAC | 863288-34-0 | 2mg/vial |
| PT-141 | lOmg/vial | |
| MT-1 | 75921-69-6 | lOmg/vial |
| MT-2(Melanotan II) | 121062-08-6 | lOmg/vial |
| GHRP-2 | 158861-67-7 | 5mg/vial |
| GHRP-2 | 158861-67-7 | lOmg/vial |
| GHRP-6 | 87616-84-0 | 5ing/vial |
| GHRP-6 | 87616-84-0 | lOmg/vial |
| Ipamorelin | 170851-70-4 | 2mg/vial |
| Hexarelin | 140703-51-1 | 2mg/vial |
| Sermorelin | 86168-78-7 | 2mg/vial |
| Oxytocin | 50-56-6 | 2mg/vial |
| TB500 | 77591-33-4 | 2mg/vial |
| pentadecapeptide BPC 157 | 2mg/vial | |
| HGH Fragement 176-191 | 221231-10-3 | 2mg/vial |
| Triptorelin | 57773-63-4 | 2mg/vial |
| Tesamorelin | 218949-48-5 | 2mg/vial |
| Goradorelin | 2mg/vial | |
| Gonadorelin | lOmg/vial | |
| DSIP | 62568-57-4 | 2mg/vial |
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Selank |
5ing/vial |
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Angiotensin |
lg/foil bag |
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Lanreotide |
lg/foil bag |
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Arelin Acetate |
lg/foil bag |
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Terlioressin Acetate |
lg/foil bag |
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SNAP-8 |
lg/foil bag |
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Exenatide acetate |
lg/foil bag |
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Fertirelina |
lg/foil bag |
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Octreotide acetate |
lg/foil bag |
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Goserelin acetate |
lg/foil bag |
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Decapeptide-12 |
lg/foil bag |
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Eveservl |
lg/foil bag |
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Thvinosin Q-l Acetate |
lg/foil bag |
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Follistatin 344 |
lmg/vial |
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Follistatin 315 |
lmg/vial |
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Eoitalon |
lOmg/vial |
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ThvrotroDin TRH |
2mg/vial |
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Adiootide |
2mg/vial |
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AOD-9604 |
221231-10-3 |
2mg/vial |
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ACE 031 |
2mg/vial |
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GDF-8 |
2mg/vial |
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Deslorelin |
lOmg/vial |
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Eptifibatide |
2mg/vial |
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Mvostatin |
lmg/vial |
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